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Jedidiah Carlson, Ph.D.

Population Genetics | Bioinformatics | Metaresearch

UCSC mutation rate browser track

Introduction

The Mutation Rate Browser is a preconfigured UCSC Genome Browser track to explore and visualize patterns of fine-scale variability in human germline mutation rates alongside other genomic data.

Download the data

The raw data used to create these tracks can be downloaded at http://mutation.sph.umich.edu/hg19/. Tracks are only available for assembly GRCh37 (hg19) of the human reference genome, but can be converted to coordinates in other assemblies using the UCSC liftOver utility. Tracks are in a compressed wiggle (BigWig) format. Because these files are quite large (~50GB total), we recommend using a download manager such as wget or curl.

Citation

If you use the Mutation Rate Browser in your research, please cite the following publication:

Carlson J, Locke AE, Flickinger M, Zawistowski M, Levy S, Myers RM, et al. Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans. Nat Commun. 2018;9: 3753. doi:10.1038/s41467-018-05936-5

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